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所在位置:所有产品 > 抗体抗原 > 一抗 > NOTCH4抗体
NOTCH4抗体图片
产品货号:
Z21721
中文名称:
NOTCH4抗体
英文名称:
Anti-NOTCH4 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-NOTCH4 Antibody
指标别名notch receptor 4;INT3;NOTCH4
克隆性Polyclonal
检验物种human
应用范围WB
基因名称NOTCH4
抗体来源Rabbit
抗体类型IgG
免疫原A synthetic peptide corresponding to a sequence at the C-terminus of human NOTCH4(1805-1818aa DVAHQRNHWDLLTL).
实际分子量210KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料NOTCH4(NOTCH,DROSOPHILA,HOMOLOG OF,4) also known as INT3 or NOTCH3,FORMERLY,is a member of the Notch family.In situ hybridization revealed that Notch4 transcripts are primarily restricted to endothelial cells in embryonic and adult life,suggesting a specific role forNotch4 during development of vertebrate endothelium.The sequences of the mouse and human NOTCH4 proteins are 82% identical.Northern blot analysis revealed that NOTCH4(S) is the major transcript and is expressed in a wide variety of tissues.Fluorescence in situ hybridization confirmed the location of the NOTCH4 gene at chromosome 6p21.3.In linkage disequilibrium mapping of the MHC region in 80 British parent-offspring trios,Wei and Hemmings(2000) found that NOTCH4 was highly associated with schizophrenia.Repression of Notch4 resolved ataxia and reversed the disease progression,demonstrating that Notch4 is not only sufficient to induce but also required to sustain the disease.
Uniprot IDQ99466
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称notch 4
蛋白名全称Neurogenic locus notch homolog protein 4(Notch 4)
推荐稀释比
Western blot(WB) 1:500~2000

相关搜索:NOTCH4抗体NOTCH4多抗Anti-NOTCH4 Antibody
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