产品货号:
Z21721
中文名称:
NOTCH4抗体
英文名称:
Anti-NOTCH4 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-NOTCH4 Antibody |
指标别名 | notch receptor 4;INT3;NOTCH4 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB |
基因名称 | NOTCH4 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human NOTCH4(1805-1818aa DVAHQRNHWDLLTL). |
实际分子量 | 210KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | NOTCH4(NOTCH,DROSOPHILA,HOMOLOG OF,4) also known as INT3 or NOTCH3,FORMERLY,is a member of the Notch family.In situ hybridization revealed that Notch4 transcripts are primarily restricted to endothelial cells in embryonic and adult life,suggesting a specific role forNotch4 during development of vertebrate endothelium.The sequences of the mouse and human NOTCH4 proteins are 82% identical.Northern blot analysis revealed that NOTCH4(S) is the major transcript and is expressed in a wide variety of tissues.Fluorescence in situ hybridization confirmed the location of the NOTCH4 gene at chromosome 6p21.3.In linkage disequilibrium mapping of the MHC region in 80 British parent-offspring trios,Wei and Hemmings(2000) found that NOTCH4 was highly associated with schizophrenia.Repression of Notch4 resolved ataxia and reversed the disease progression,demonstrating that Notch4 is not only sufficient to induce but also required to sustain the disease. |
Uniprot ID | Q99466 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | notch 4 |
蛋白名全称 | Neurogenic locus notch homolog protein 4(Notch 4) |
推荐稀释比 | Western blot(WB) 1:500~2000 |
相关搜索:NOTCH4抗体,NOTCH4多抗,Anti-NOTCH4 Antibody